(Reuters) - Taiwan's Acer Inc will buy U.S.-based cloud computing firm iGware Inc for $320 million, the fifth-largest ever Taiwanese buyout of a U.S. company, as it seeks to move beyond its core hardware manufacturing business.

The world's No.2 PC maker said it was also in initial talks with Japanese game firm Nintendo, a major client of iGware, over potential cooperation after the deal, but did not give details.

Acer has been refocusing on mobile devices to drive future growth after a troubled first half that saw the acrimonious departure of its chief executive after a row over the company's strategy and a series of cuts to its shipment forecasts.