Telegram is a free mobile/desktop messaging app with a focus on speed and security.

Trillian is a multi-network chat client that supports Google, AIM, ICQ, Twitter, and more.

Ferdium offers an innovative online platform that serves as a one-stop shop for a wide range of communication services. A Portable version via PortableApps is also available.

Viber is a cross-platform VoIP (voice over IP) application that will let you send free messages and make free calls to other Viber users on any device, network, or in any country in which you happen to be.

Signal Private Messenger allows you to communicate in real-time and share media or attachments with complete privacy.

Discord is a popular instant messaging and VoIP app offering data and traffic protection for desktop computers and smartphones. There is an Open Source portable version available.

Session is a secure messenger that provides complete end-to-end encryption to ensure privacy and removes sensitive metadata.

If you're looking for a portable way to access Zoom for virtual meetings and collaboration, look no further than zmPortable. Installer is also available.

Microsoft Teams allows you to invite anyone you work with to chat, meet, call, and collaborate all in one place, no matter where you are.

WhatsApp for Desktop provides you with nearly all the same free functionality of the Android version directly on your PC.

TeamTalk allows you to chat with your friends or colleagues using the internet or a local area network.

Chatterino is a specialized chat client for Twitch that offers a more advanced and user-friendly experience than the standard Twitch web chat.

Monochrome is an IRC client intended for long-time IRC users with the goal of security, reliability, and stability despite IRC network failures or connectivity problems.

Zoom Workplace can help you connect with friends and coworkers, featuring chat, meetings, video webinars, conference rooms, and more. A portable version is also available.

Jami is a viable alternative to Zoom that is designed with the freedom and privacy of users in mind.

MicroSIP is a free, Open-Source app that allows you to easily make high-quality VoIP calls (person-to-person or on regular telephones) via the open SIP protocol.

Discord Portable lets you take the popular Discord instant messaging and VoIP app with you.

SplitCam offers cool webcam effects for having more positive emotions during video calls with your friends.

Rambox is an Open Source messaging and emailing app that combines the most common web applications into one.

Logi Tune provides you with a way to optimize your webcam and Logi Dock for video meetings.

Netchat allows you to chat with other users in the same subnet easily.

Camfrog Video Chat is a free cross-platform app that lets you instantly jump into live video‑chat rooms or start private video calls.

Ferdium Portable provides an innovative online platform that functions as a service consolidator. It allows you to access a wide range of communication services in one place. It is also available as an installer and for Linux and Mac.

Skype is one of the longest-running, well-known video chat clients. Also available as a portable app.

sPortable allows you to take Skype with you wherever you may roam. Skype desktop, Android, and Mac are also available.