Viber is a cross-platform VoIP (voice over IP) application that will let you send free messages and make free calls to other Viber users on any device, network, or in any country in which you happen to be.
RetroMessenger is an innovative messaging application inspired by the iconic interfaces from Sci-Fi films that offers you secure, encrypted peer-to-peer connections, ensuring that conversations remain private and protected.
Discord is a popular instant messaging and VoIP app offering data and traffic protection for desktop computers and smartphones. There is an Open Source portable version available.
If you're looking for a portable way to access Zoom for virtual meetings and collaboration, look no further than zmPortable. Installer is also available.
Zoom Workplace can help you connect with friends and coworkers, featuring chat, meetings, video webinars, conference rooms, and more. A portable version is also available.
Mumble is a low-latency, always encrypted Open Source communication application perfect for gamers with an in-game overlay as well as positional audio so you can hear where other players are located. A portable version is also available.
Monochrome is an IRC client intended for long-time IRC users with the goal of security, reliability, and stability despite IRC network failures or connectivity problems.
MicroSIP is a free, Open-Source app that allows you to easily make high-quality VoIP calls (person-to-person or on regular telephones) via the open SIP protocol.